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From 1995 until 2000,
McLaren served as Group Leader for Chemical Metrology in INMS. Many
of the activities of this group are aimed to assist analytical
laboratories in both the public and private sectors in assuring the
accuracy of determinations of inorganic and organic contaminants in
environmental samples. These activities include the development of
reliable methodologies, the provision of certified reference
materials and the co-ordination of laboratory proficiency testing
exercises. He also became increasingly active in international
metrology activities that are co-ordinated under the auspices of the
International Committee of Weights and Measures.
Dr. McLaren acquired a broader knowledge of NRC during a 2-year
period from 1997-1999, when he served as Leader of the NRC
Competency Project, the objective of which was to implement
competency-based human resources management at NRC. He is currently
a member of the Human Resources Management Steering Committee, which
serves as an advisory board to the Human Resources Branch.
Dr. McLaren was appointed INMS Director, Chemical and Mechanical
Standards in January 2000, assuming responsibility for INMS
activities in chemical metrology, dimensional metrology, mass
standards, acoustical standards and time and frequency metrology.
Following a re-organization of INMS in late 2004, he successfully
competed for his current position.
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Opening Address
v Dr.
Roman Szumski,
Vice-President, Life
Sciences, National
Research Council of Canada
Dr. Roman Szumski's Bio:
The In 2005, Dr. Roman
Szumski was appointed the National Research Council's Vice-President,
Life Sciences. A medical doctor and pathologist by training, Dr. Szumski is recognized
as a visionary leader and an innovative manager with unique experience
in building strategic public-private sector partnerships in the life
sciences sector. He was the founding CEO of Calgary Laboratory Services,
and more recently Vice-President (Science & Technology) of MDS Inc. During his years at MDS headquarters, Dr. Szumski held executive-level
responsibility for scientific assets of the firm, with more than 10,000
employees, $1.8 billion in annual sales and diverse international
business interests. While at MDS, he also led the development of new
business initiatives in cancer therapeutics and personalized medicine. As
a founding CEO of Calgary Laboratory Services, and as a President of a
private firm,
Dr. Szumski championed and built a new collaboration between the Calgary
Regional Health Authority and the
private sector that facilitated major improvements in service and
efficiency in the services offered through seven public and private
sector labs. His career at Calgary Medical Laboratories included the
roles of pathologist, director of microbiology, and medical
director. He also worked in the Department of Pathology at the
University of Calgary. Dr. Szumski is a Fellow of the Royal College of Physicians and Surgeons
of Canada, and he holds degrees from Queen's and McGill universities.
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Keynote Address: Medical Devices and
Blood Pressure Measurement Technology
v Dr. Tofy
Mussivand, Chair and Director
of Cardiovascular Devices Division, University of Ottawa Heart Institute
Professor, Surgery and Engineering, Medical Devices Program, University
of Ottawa and Carleton University
Dr. Tofy Mussivand’s Bio:
Dr. Tofy Mussivand
received his undergraduate education and training in engineering
and management. Following many successful years in senior
positions in government, crown corporations, and the private
sector, Dr. Mussivand went on to receive his doctorate in
Medical Engineering and Medical Sciences at the University of
Akron and Northeastern Ohio Universities College of Medicine.
Thereafter, Dr. Mussivand joined the internationally acclaimed
Cleveland Clinic Hospital and Research Foundation where he
gained invaluable knowledge and experience in the development of
medical devices, artificial hearts, and cardiac care. In 1989,
Dr. Mussivand was invited to return to Canada to continue his
pioneering work in the field of medical devices.
Dr. Mussivand has achieved both national and global recognition.
His breakthroughs have resulted in the establishment of
scientific eminence for Canada in the fields of medical devices,
artificial hearts, remote power transfer, in situ sterilization,
etc. Presently, he is Professor of Surgery and Engineering at
the University of Ottawa and Carleton University; Chair and
Director, Cardiovascular Devices Division of the University of
Ottawa Heart Institute (UOHI); and Medical Devices Program of
both the University of Ottawa and Carleton University.
Combining his scientific, management, and business expertise,
Dr. Mussivand has been the Chairman of several boards, member of
various Boards of Directors, and the CEO of several successful
corporations. His leadership has been responsible for the
creation of over 1000 man-years in the Canadian work force and
has been the catalyst for an influx of more than $200 million,
primarily from outside of Canada, during the last ten years.
Dr. Mussivand's areas of interest and contributions include
artificial hearts (mechanical circulatory support devices) as
treatment for heart failure, remote power transfer for
implantable medical devices, remote patient monitoring
(telemedicine), biofluid dynamics to reduce/eliminate thrombosis
in blood conducting devices, patient care simulation centre,
detection devices and methods for detection, in situ
sterilization, medical devices (failure analysis and regulatory
process), and medical sensors.
Dr. Mussivand has published over 250 papers, books, and
technical articles and supervised and taught over 300 students,
residents, and postdoctoral Fellows.
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Message from the Moderator: The
Ottawa-Carleton Institute for Biomedical Engineering Initiatives and
Programs
v Dr.
Rafik Goubran,
Acting Dean, Faculty of Engineering and Design, Carleton University,
Ottawa
Dr. Rafik Goubran's Bio:
Dr. Goubran is currently Professor and Acting Dean of Faculty of
Engineering and Design at Carleton University. Dr. Goubran was born in
Cairo, Egypt, in 1955. He received the B.Sc. and M.Sc. degrees in
Electrical Engineering from the department of Electronics and
Communications Engineering, Cairo University, Cairo, Egypt, in 1978 and
1981 respectively. He received the Ph.D degree in Electrical Engineering
from the Department of Systems and Computer Engineering, Carleton
University, Ottawa, Canada, in 1986. In January 1987, he joined the
Department of Systems and Computer Engineering, Carleton University,
Ottawa, Canada, where he is now professor and Chair. He is a member of
IEEE and the association of Professional Engineers of Ontario. He acted
as a consultant to several industrial and government organizations
including Nortel, Mitel, Bell Canada, Vienna Systems (Nokia), Revenue
Canada, the Department of National Defense (DND), Bota Teleconferencing,
Matcom, the National Research Council of Canada (NRC), and Data
Measurement Corporation, U.S.A. His research interests include: Digital
Signal Processing (DSP) and its applications in acoustics, speech
processing, communications, and analytical chemistry. Voice transmission
over IP (VoIP) and ATM networks. Current research projects deal with
audio quality improvement in telephony, audio teleconferencing, acoustic
echo and noise cancellation, adaptive filter structures, beam forming
using microphone arrays, and narcotics detection using ion mobility
spectrometry. Other interests include mobile communications, digital
systems design, DSP hardware, multiprocessor architectures for DSP, and
computer architecture.
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IEEE Standardization of Blood Pressure
Measurement Initiative
v Dr.
Voicu Groza, Professor,
School of Information Technology and Engineering, University
of Ottawa, Ottawa
Abstract:
Debates over the
most widely measured vital sign – blood pressure – over the past 100
years are entwined with a core methodological question: ‘How blood
pressure should be measured?’ While there are numerous standards for
blood pressure measurement, none of them rely on a logically consistent
and mathematically competent measurement theory. There are a number of
promising approaches to routine blood pressure measurement and the
calibration of automatic blood pressure meters, but all of them run into
difficulties with the object and objective of measurement. The medical
interpretation of blood pressure measurement remains therefore
problematic. Recent advances in instrumentation and measurement,
however, provide the theoretical and technical support for advancing
blood pressure measurement beyond the limits of the century-old Korotkov
technique. It is now possible to standardize blood pressure measurement
without any reference to habit and skill. To that end, enthusiast
members of the IEEE Instrumentation and Measurement Society have founded
a Group for the Standardization of the Blood Pressure Measurement in the
frame of the IEEE TC-25 Technical Committee of Medical and Biological
Measurements. The goals and the plans of the newly constituted
subcommittee are presented.
Dr. Voicu Groza’s Bio:
Voicu Z. Groza
received the Dipl. Eng. degree in computer engineering in 1972 and his
Doctor of Engineering degree in electrical engineering in 1985, both
from the Polytechnic Institute of Timisoara, Romania. He was a professor
in the Department of Computer Engineering of the Polytechnic University
of Timisoara, Romania, and in 1997, he joined the School of Information
Technology and Engineering at the University of Ottawa, Canada. His
research interests include quantization theory, distributed intelligent
instrumentation and reconfigurable computers. Dr. Groza is the author or
coauthor of more than 150 technical papers and 2 patents in these areas.
He is a Senior Member of the /IEEE Instrumentation and Measurement
Society/ and he is currently serving as a Chair of the Ottawa Chapter of
this society. Dr. Groza is a founding member of the Subcommittee on
Standardization of Blood Pressure Measurement/, in the frame of the
/IEEE TC-25 Technical Committee of Medical and Biological Measurements/
of the /IEEE Instrumentation and Measurement Society/. He is also a
member of the /IEEE Standards Association/, /IEEE Engineering in
Medicine and Biology Society/, and /IEEE Computational Intelligence
Society/. Dr. Groza served as a technical program chair or co-chair of
several major international conferences such as /IEEE International
Conference on Instrumentation and Measurement /(IMTC 2005), /IEEE
Canadian Conference on Electrical and Computer Engineering/ - CCECE
2006, /IEEE International Workshop on Haptic Virtual Environments and
their Applications/ - HAVE 2004.
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Health
Canada's role in regulation and standards for blood pressure instruments
v Dr.
Philip D. Neufeld, Manager of
the Device Surveillance Division of the Medical Devices Bureau, Health
Canada
Abstract:
Blood pressure instruments are regulated as medical devices under the
Food and Drugs Act. The Medical Devices Bureau has conducted research
into the accuracy required of these devices to provide reliable blood
pressure determinations, and the accuracy with which health care
professionals can use them. This talk describes some early research
studies, current standards for blood pressure instruments, and Health
Canada's licensing procedure for these devices.
Dr. Philip Neufeld’s Bio:
Philip D. Neufeld is Manager of the Device Surveillance Division of the
Medical Devices Bureau,
Health Canada, which he joined in 1975. He holds a doctorate in physics
from the University of Waterloo, Ontario. As Manager of Device
Surveillance, he directs the Bureau's activities in laboratory research,
testing, and post-market surveillance of medical devices. He conducted
research and co-authored two publications on blood pressure measurement,
and wrote
a standard under the Medical Devices Regulations for the accuracy of
sphygmomanometers.
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The Measurement
Problem in Medicine: the Case of Hypertension
v Dr.
Radu Leca, CTO, Biosign
Technologies Inc., Toronto
Abstract:
Measurement-related illness has become a scandalous
pandemic. It is now a top cause of morbidity and mortality, particularly
in the elderly. The extent of this pandemic is described and its main
effects in primary care are identified using the case of hypertension –
a major reason for visiting a physician. Urgent action by scientists and
engineers is recommended under two headings: measurement and
standardization.
Dr. Radu Leca’s Bio:
Radu Leca is a senior
biomedical researcher at Biosign Technologies. As a physician, his early
work focused on the notion of health and the means of diagnostic
optimization. He has recently contributed to the development of a range
of new concepts and methods to strengthen the technological basis for
autonomous medical care.
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Modeling the Human Cardiovascular System
v Dr. Aneta Stefanovska,
Lancaster University, Lancaster,
UK
Abstract:
Contemporary measurement techniques enable noninvasive observations of
cardiovascular functions, both from the central and peripheral points of
view. Cardiovascular dynamics is found to be characterized by several
distinct frequency components, and these are present at each site of the
system. The corresponding oscillatory processes are mutually dependent
via couplings that lead to amplitude/frequency fluctuations of the
characteristic peaks. We describe analysis of several non-invasive
simultaneous measurements of cardiovascular signals in healthy subjects
of all age and in patients with cardiac failure, diabetes and after
acute myocardial infarction. Using phase dynamics approach we then
introduce model of the human cardiovascular system based on the coupled
nonlinear oscillators. coupled oscillators, cardiovascular oscillations,
time-frequency analysis, interactions, synchronization, blood flow,
blood pressure, heart rate variability, endothelial vasoregulation.
Dr. Aneta Stefanovska’s Bio:
Aneta Stefanovska completed her PhD in 1992 combining biocybernetics and
synergetics, working partly in Ljubljana and partly in Stuttgart. She
then introduced the coupled oscillators approach to cardiovascular
dynamics and invested much energy in the improvement of data acquisition
and analysis. She headed the Nonlinear Dynamics and Synergetics Group in
Ljubljana from 1993. In 2006 she came to Lancaster University as Reader
in Medical Physics where she is developing major new initiatives
involving the application of nonlinear dynamics to biology and medicine.
Aneta Stefanovska is with the Department of Physics, Lancaster
University, Lancaster and in part with the Nonlinear Dynamics and
Synergetics Group, Faculty of Electrical
Engineering, University of Ljubljana, Ljubljana, Slovenia.
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Photonics
Methods for Imaging Blood Flow and Oxygen Delivery
v Dr.
Michael Sowa, Senior
research officer and leader of the Optical Spectroscopy Group, Institute
for Biodiagnostics (IBD), National Research Council of
Canada's (NRC),
Winnipeg
Abstract:
The National Research Council of Canada (NRC) has helped develop a
number of photonics-based imaging methods to determine regional blood
perfusion and oxygen delivery. These technologies and their applications
in the areas of coronary perfusion, wound assessment, surgical
reconstruction and peripheral vascular sufficiency will be presented.
Dr. Michael (Mike) Sowa’s Bio:
Dr. Mike Sowa is a senior research officer and leader of the Optical
Spectroscopy Group at the National Research Council of Canada's (NRC)
Institute for Biodiagnostics (IBD) in Winnipeg. He joined NRC's Steacie
Institute for Molecular Sciences (SIMS) as a postdoctoral fellow in
1990, shortly after completion of his Ph.D. in physical chemistry at the
University of Manitoba. In 1992 he joined the nascent Institute for
Biodiagnostics in Winnipeg to help establish a research program in
biomedical vibrational spectroscopy, a program which he now leads. His
research interests are targeted at developing medical applications using
optical and infrared spectroscopy and translating these developments
into clinical practice. Current research activities include the
development of near infrared spectroscopic imaging methods to assess
acute and chronic wounds. Since 2004, he has been managing NRC's
Genomics and Health Initiative program, Managing Chronic Cardiovascular
Disease, in which new optical and magnetic resonance imaging methods are
being developed to study coronary perfusion, atherosclerosis and
myocardial injury and repair.
Physiological
basis of Oscillometric Blood Pressure Measurement
v Jiri
Jilek, MS, King/Drew Medical
Center, Los Angeles, US
Abstract:
The oscillometric
method as used today evaluates oscillometric waveform (OMW) amplitudes
and cuff pressures to determine systolic (SBP), diastolic (DBP) and mean
(MAP) arterial pressures. The determination of MAP is based on vascular
unloading. MAP is determined as the cuff pressure at the point of
maximal OMW amplitude. SBP and DBP values are determined by a variety of
empirically developed algorithmic methods that are not based on the
underlying physiology. My studies of OMWs resulted in an attempt to
explain the physiology of oscillometric SBP and DBP in terms of the
effect blood flow exerts on vascular unloading.The SBP hypothesis states
that the slope of OMW amplitude envelope between reference SBP and MAP
(S2) is less steep than either the slope (S1) at CPs higher than
reference SBP or the slope (S3) between MAP and reference DBP. The
transition of S1 to S2 is the point where SBP should be determined.
Study of 32 subjects supported the hypothesis. The DBP hypothesis states
that the point on the OMW envelope where OMW contour distortions
disappear is where DBP should be determined. Data supporting the DBP
hypothesis are still being gathered. The flow-based observations are in
accordance with the Korotkoff sounds (auscultatory) method. Algorithms
recognizing changes in the slopes and algorithms recognizing the
transition from distorted to distortion-free OMW contours could improve
accuracy of oscillometric blood pressure determination.
Jiri Jilek’s Bio:
Mr. Jiri Jilek
received MSEE degree from University of Southern California (USC), Los
Angeles in 1972. From 1972 to 1981 worked as research engineer at USC-Medical
Center, Los Angeles, in the field of perinatal medicine. Research
projects included a method for evaluation of fetal heart rate
variability and an on-line system for evaluation of fetal heart rate
patterns. From 1982 to 1989 worked as an independent consultant in the
field of medical engineering. Projects included design of pulmonary
function monitor and a personal computer based blood pressure monitor.
From 1989 to 1997 worked as research engineer at Drew University of
Medicine and Science, Los Angeles. Projects included development of an
experimental system for evaluation of maternal cardiovascular parameters
and data acquisition from fetal monitors. From 1997 to the present time
has worked at King-Drew Medical Center, Los Angeles as a senior R&D
engineer. He has also worked as an independent engineering consultant.
Research projects included processing of digital arterial waveforms,
development of a system for noninvasive evaluation of blood pressures
and hemodynamics, and a new method for bench-testing of blood pressure
monitors. Mr. Jilek published numerous journal and conference papers. In
2002 he became a member of the Association for Advancement of Medical
Instrumentation (AAMI). Main professional interests are in medical
engineering and they include design of analog and digital systems,
software development, and research of oscillometric blood pressure
waveforms.
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Medical standards for medical data
communication: IEEE 1073 and HL7
v Dr.
ir. Nick Goga, Royal
University of Groningen, the Netherlands
Abstract:
The scope of ISO/IEEE 1073 family of standards is to provide open
systems communications in healthcare applications, primarily between
bedside medical devices and patient care information systems, optimized
for the acute care setting. Working in the same area as ISO/IEEE 1073,
HL7 is an ANSI accredited standard in the area of healthcare and
information science that aims to standardize the exchange, management
and integration of electronic healthcare information. This presentation
will outline some key elements of the two standards for medical
information exchange trying to give an inside in this world of medical
information exchange..
Dr. ir Nick Goga’s Bio:
Dr. N. Goga holds two doctorates: one in Science from the Technical
University of Eindhoven, the Netherlands, and one in Computer Science
from the Polytechnic University of Bucharest, Romania. Since 2003 he is
a member of the general committee of the ISO/IEEE 1073 standards of
medical data communication. Also, he is a honorary president of the HL7
Romania, the Romanian national HL7 association affiliated to HL7
International. HL7 is an ANSI standard for medical data communication.
Currently, Dr. Goga works as a researcher in the MD group of the Royal
University of Groningen, the Netherlands.
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Technological
Challenges in Developing Motion & Noise Tolerant Automated Blood
Pressure Devices
v Dr.
Stergios Stergiopoulos, Chief
Scientist CANAMET Inc., Defence Research and Development Canada
v Dr.
Uri Sagman, MD, FRCPC,
Executive Director, The Canadian NanoBusiness Alliance
Abstract:
Current system
concepts for non-invasive monitoring of vital signs are limited in
providing reliable blood pressure estimates in vibration & noise intense
environments. Although the accuracy of high end blood pressure systems
is considered to be sufficient, in most emergency and search and rescue
operations, the lack of accuracy of these vital signs measurements makes
the relevant system concepts unattractive to medical practitioners.
CANAMET Corporation has overcome some of these limitations by using
advanced signal processing techniques that include adaptive interference
cancellation and pattern recognition algorithms. The use of these
advanced signal processing techniques leads to a feasible system for
providing vital sign measurements in challenging noisy environments,
such as ambulances and helicopters.
The scope of the presentation is to briefly review the various blood
pressure estimation techniques and the technological challenges in
developing motion & noise tolerant blood pressure devices. Furthermore,
it will review also the clinical testing procedures and issues
relevant with FDA-510K, CSA, CE regulatory approvals.
Dr. Stergios Stergiopoulos’s Bio:
Stergios Stergiopoulos, Ph.D., (Senior member of IEEE and Fellow of
Acoustical Society of America) Received the B.Sc. degree from the
University of Athens in 1976 and the M.Sc. & Ph.D. degrees in geophysics
in 1977 and 1982, respectively, from York University, Toronto, Canada.
Presently, he is an Adjunct Research Professor at the Department of
Electrical & Computer Engineering of the University of Western Ontario,
the founder of CANAMET Inc. and the main innovator of the Defence R&D
Canada (DRDC) technologies and patents that have been licensed to
Canamet Inc (www.canamet.com). These innovation include a number of
non-invasive 3D imaging (i.e. cardiac 3D CT, portable 3D/4D ultrasound)
and vital signs monitoring (i.e. motion & noise tolerant automated blood
pressure & intracranial ultrasound) technologies. To complete their
development and their commercialization process, Dr. Stergiopoulos
raised approximately $11 million from private investors and Government
grants. He has an extensive background in science and research. From
1991 to 2003 he was a Senior Defence Scientist at the Defence R&D
Canada. From 1988 to 1991, he was with the NATO SACLANT Centre in La
Spezia, Italy, where he performed both theoretical and experimental
research in sonar signal processing. At SACLANTCEN, he developed jointly
with Dr. Sullivan from NUWC an acoustic synthetic aperture technique
that has been patented by the U.S. Navy. From 1984 to 1988 he developed
an underwater fixed array surveillance system for the Hellenic Navy in
Greece and there he was appointed also senior advisor to the Greek
Minister of Defence. From 1982 to 1984 he worked as a research associate
at York University and in collaboration with the U.S.Army Ballistic
Research Lab (BRL), Aberdeen,MD, on projects related to the stability of
liquid filled spin stabilized projectiles. In 1984 he was awarded a U.S.
NRC Research Fellowship for BRL. He was Associate Editor for the IEEE
Journal of Oceanic Engineering. He has published numerous scientific
articles and a Handbook (i.e. CRC-Press) in the areas of advanced signal
processing for sonar and medical non-invasive system applications. He
has been awarded with European Commission-IST grants as technical
manager of several projects that included as project partners major
European corporations and Institutes (i.e. Siemens, Nucletron, Philips,
Sema Group, Esaote, Atmel, Fraunhofer). These project were entitled “New
Roentgen”, “MITTUG”, “ADUMS”, “MRI-MARCB”, “DUST” and Euroworkshop
“Fourier” and their budget level was of the order of Euro 1.5 million
each. Dr. Stergiopoulos is a Fellow of the Acoustical Society of America
and a senior member of the IEEE. He has been a consultant to a number of
companies, including Atlas Elektronik in Germany, Hellenic Arms Industry
and Hellenic Aerospace Industry.
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Dr. Uri Sagman’s Bio:
Dr. Sagman is
a medical oncologist, a fellow of the Royal College of Physicians and
Surgeons of Canada, and a fellowship recipient of the Medical Research
Council of Canada. He is a recognized researcher in the field of
clinical oncology, tumor biology and immunology. Dr. Sagman obtained his
training at McGill University, The University of Calgary, The University
of Toronto and Oxford University.
Dr. Sagman is the co-founder and Executive Director of the Canadian
NanoBusiness Alliance, an association dedicated to the promotion of the
nanotechnology sector in Canada. The Canadian NanoBusiness Alliance has
a diverse membership, which includes representation of government
agencies, academic centers of excellence, industry and the investment
community.
Dr. Sagman is cofounder and past President and CEO of C Sixty Inc. At C
Sixty, Dr. Sagman has recruited some of the world's leading scientists,
including the 1996 Nobel Prize awardee and co-discoverer of fullerenes,
to advance the development of fullerene-based technology for biomedical
applications. To that end, Dr. Sagman has enlisted a comprehensive R&D
network, based at leading academic centers, which include Rice
University, UCLA, Columbia University, Dartmouth University, the
University of Toronto, Erlangen University in Germany, and the
University of Taiwan.
Dr. Sagman is the Chairman of GRN Health International Inc., a globally
based academic research organization dedicated to medical research and
development. Dr. Sagman is the founder and chairman of GRN Capital Inc.,
a financial services corporation with merchant banking and investment
banking operations based in Toronto , Canada. Dr. Sagman is currently
engaged in the development of strategies for National Nanotechnology
Initiative programs in several countries, specializing in the
development of paradigms for public and private sector alliances. In
addition, Dr. Sagman's efforts are focused on the application of
nanotechnology to problems of global scope.
Dr. Sagman is the recipient of numerous awards and citations including
the Young Investigator awards of the American Society of Clinical
Oncology (ASCO) and the American Association for Cancer Research (AACR).
He has organized and participated as keynote speaker at numerous
nanotechnology-based conferences. Dr. Sagman has been extensively
profiled in numerous journal and press publications, including Time
Magazine, Newsweek, The Economist, the New York Times, Red Herring,
Technology Review, Chemical Engineering, the National Post, the Houston
Chronicle, and The Toronto Star amongst others.
È
Determination of
Ventricular Pressure and Ventricular Load in the Presence of an Aortic
stenosis
v Dr.
Lyes Kadem,
Dept. of Mechanical and Industrial Engineering, Concordia University,
Montreal
Abstract:
In developed countries, aortic valve stenosis is the most common heart
valve disease. Aortic stenosis causes an obstruction to blood flow from
the left ventricle to the ascending aorta, as a consequence, the left
ventricle has to face an extra load.
The most important parameters used to determine the extra load supported
by the left ventricle in the presence of an aortic stenosis use as an
input the systolic ventricular pressure. In this presentation, we will
show how this pressure can be determined non-invasively using
mathematical models and a limited number of parameters measured using
Doppler echocardiography.
We will also introduce, in this presentation, a mathematical model to
determine the coronary input pressure in the presence of an aortic
stenosis..
Dr. Lyes Kadem’s Bio:
Dr. Lyes Kadem received his engineering degree [1998] in mechanical
engineering from Univeristé des Sciences et de la Technologie Houari
Boumediene, Algiers, Algeria, his master degree and his Ph.D [2004] in
biomechanics from Ecole Superieure de Mecanique de Marseille (ESM2);
Marseille; France, and another Ph.D [2004] in experimental medicine from
Laval University; Quebec; Canada.
From 2004 to 2006, Dr. Lyes Kadem joined as postdoctoral fellow the
BioEngineering Laboratory at Institut de Recherches Cliniques de
Montreal.
He is currently assistant professor at the department of Mechanical and
Industrial Engineering; Concordia University; Montreal; Canada.
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